西北大学学报(自然科学版)

2002, 05, 561-563

运动对大鼠骨骼肌及血清GH,IGF-I水平研究

1.西北大学体育部,西安交通大学体育部陕西西安　710069 ,陕西西安　710049

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摘要：

生长激素(GH)、胰岛素样生长因子I(IGF-I)都是了解GH-IGF轴变化的主要指标。IGF不仅是内分泌因子,还能在组织局部起作用。通过对6周递增负荷跑台练习的大鼠进行研究,结果显示:运动后即刻处死的大鼠血清GH水平明显升高(P<0.01);运动组与对照组相比,骨骼肌IGF-I水平有明显升高(P<0.01),表明运动对骨骼肌组织内IGF的分泌有调节作用。

关键词： 递增负荷训练; 生长激素(GH); 胰岛素样生长因子I(IGF-I);

Abstract：

GH and IGFI as the member are important to understand the biological action of GHIGF axis.IGF not only are endocrinic factors,but have their roles in local tissue.A study on rats after sixweek incremental running exercise showed that the serum GH concentrations at immediately post exercise were significantly higher (P<0.01). The skeletal muscle IGFI concentrations in trained rats were significantly higher with their controls (P<0.01). This indicates that exercise can influence the autocrine/paracrine acting IGF of skeletal muscle.

KeyWords： incremental exercise; growth hormone (GH); insulinlike growth factor I (IGFI);

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参考文献

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[1]徐国营,刘迅雷.运动对大鼠骨骼肌及血清GH,IGF-I水平研究[J].西北大学学报(自然科学版),2002(05):561-563.

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西北大学学报(自然科学版)

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